How It Works
Life’s not always easy – especially on your skin. You’ve earned each and every one of those wrinkles. Late nights, long golf outings, and kids all impact the appearance of your skin. And getting older doesn’t help either. Aging skin loses natural support structures (collagen and elastin) that keep skin supple and youthful. As the years go by, the support structures of the skin diminish, and the skin loses its ability to bounce back. Wrinkles and creases are the unfortunate result.

But now there’s a way to hide the years of misuse and abuse on the skin. Injectable fillers are used to plump the skin and erase evidence of a well-lived life. Wrinkle fillers are a minimally invasive procedure that your healthcare provider can administer in-office, over a lunch hour. Using a fine gauge needle, your healthcare provider will inject the filler under the skin, to rejuvenate your tired skin instantly! RADIESSE® Volumizing Filler is an ideal choice to do just that. Not only does it provide immediate volume, but RADIESSE Volumizing Filler also stimulates the production of your own natural collagen.1 Only RADIESSE Volumizing Filler works in such a way that it can immediately fix facial wrinkles, and continue to provide structure over time, with results that last a year or more in many patients.2,3

Ideal for a Man’s Rugged Skin
Made from an exclusive, natural mineral, RADIESSE Volumizing Filler is injected through a fine needle and placed under the skin. Immediately, the filler works to add volume under the skin and instantly hide the signs of wrinkles and creases. Over time, as the mineral begins to break down, the benefits of RADIESSE Volumizing Filler continue as your own natural collagen is stimulated, providing additional structure after the initial effects of RADIESSE Volumizing Filler have diminished.1 The treatment’s results are both immediate and long-lasting, providing wrinkle relief for up to a year or more in many patients.2,3 The incredible lifting capacity of this exclusive, natural mineral makes RADIESSE Volumizing Filler perfect for smoothing wrinkles and folds of a man’s rugged skin.

Mechanism of Action

RADIESSE® Volumizing Filler is composed of Calcium Hydroxylapatite (CaHA) microspheres suspended in an aqueous gel carrier.1

Once injected, it provides immediate volume and correction but continues to work by stimulating the body to produce its own natural collagen.1

Over time, the gel is absorbed and the body metabolizes the CaHA microspheres leaving behind only your own natural collagen.1

Why choose RADIESSE® Volumizing Filler?

• It is the only injectable filler that immediately replenishes lost volume and stimulates the production of your own natural collagen1
• It is clinically proven to last a year or more in many patients2,3
• RADIESSE patients are significantly more satisfied than patients treated with other leading wrinkle fillers2,4
• It is FDA approved to mix with lidocaine to significantly reduce injection-related pain

Treatment with RADIESSE Volumizing Filler is quick, comfortable, and convenient, with immediately visible, long-lasting results.2,3 Ask your healthcare provider about long-lasting, wrinkle-free correction with RADIESSE Volumizing Filler, today.2,3

What are RADIESSE® and RADIESSE® (+)?
RADIESSE® and RADIESSE® (+) are dermal fillers that are used for smoothing moderate to severe facial wrinkles and folds, such as nasolabial folds (the creases that extend from the corner of your nose to the corner of your mouth).

RADIESSE® and RADIESSE® (+) IMPORTANT SAFETY INFORMATION

Who should not use RADIESSE® or RADIESSE® (+)?
You should not use RADIESSE® or RADIESSE® (+) if you have an allergy to any component of the product, if you have a history of severe allergies, if you have a bleeding disorder, or if you are pregnant or breastfeeding. You should not use RADIESSE® (+) if you have an allergy to lidocaine or medicines like it.

What is the most important information I should know about RADIESSE® and RADIESSE® (+)?
One of the risks with using these products is unintentional injection into a blood vessel. The chances of this happening are very small, but if it does happen, the complications can be serious, and may be permanent. These complications, which have been reported for facial injections, can include vision abnormalities, blindness, stroke, temporary scabs, or permanent scarring of the skin. If you have changes in your vision, signs of a stroke (including sudden difficulty speaking, numbness or weakness in your face, arms, or legs, difficulty walking, face drooping, severe headache, dizziness, or confusion), white appearance of the skin, or unusual pain during or shortly after treatment, you should notify your health care practitioner immediately.

As with all procedures that involve an injection through the skin, there is a risk of infection.

Do not use RADIESSE® or RADIESSE® (+) if you have a skin infection until it has healed.

It is not known if RADIESSE® or RADIESSE® (+) is safe or effective in the lips, or in the area around the eyes.

The microspheres in RADIESSE® and RADIESSE® (+) can be seen in X-rays and CT Scans. It is very important that you tell your health care provider that you have had RADIESSE® or RADIESSE® (+) dermal filler injected into your face.

If you have a history of herpes, you may experience a herpes breakout after receiving RADIESSE® or RADIESSE® (+).

You should minimize strenuous activity and avoid extensive sun or heat exposure for about 24 hours after treatment and until any swelling or redness has resolved.

What should I tell my doctor before using RADIESSE® or RADIESSE® (+)?
Tell your health care provider if you are taking blood thinners or medicines that can interfere with the clotting of blood, such as aspirin or warfarin. These medicines might make it more likely that you will experience bruising or bleeding at the injection site. Tell your health care provider if you have a history of forming large, raised scars or if you have had any other skin treatments such as skin peels.

What are the most common adverse events with RADIESSE® or RADIESSE® (+)?
The most common adverse events seen in clinical studies of RADIESSE® or RADIESSE® (+) include bruising, redness, swelling, pain, itching and other local side effects.

These are not all of the possible side effects with RADIESSE® or RADIESSE® (+). Merz collects information about adverse events seen with RADIESSE® and RADIESSE® (+) post-approval. These events are included in the RADIESSE® and RADIESSE® (+) Patient Information Guide based on an assessment of seriousness and potential causal relationship to RADIESSE® or RADIESSE® (+). Please see the Patient Information Guide available at www.Radiesse.com for a list of these events. Tell your health care provider about any side effects that bother you or do not go away.

Important: For full safety information, please visit www.Radiesse.com or call Merz Aesthetics Customer Service at 866-862-1211

RADIESSE® and RADIESSE® (+) are available by prescription only.